Sunday, November 15, 2009

Risk factor of colorectal cancer

The main cause of malnutrition is adopted.

As causes of colon cancer is considered part of the diet. It is assumed that high-fat meat thereby increasing the risk of diet low in fiber. Although this hypothesis has not been definitively proved, the indication of their accuracy but quite clear. Other risk factors are also counted and alcohol addiction, asbestos, and the frequent consumption of nitrosamines, for example in the form of cured one assumes that about 80 to 90 percent of colorectal diseases are due to nutritional and environmental factors. The risk of cancer increases from the 45th year of life.

Adenomas or colon polyps can become malignant.

People who have benign tumors of the colon (called adenomas), one also speaks of intestinal polyps, there have a certain risk that cast them as a malignant tumor and thus into a cancer. If such a benign tumor, for example during a colonoscopy, found, we recommend the removal of the adenoma or during the investigation, e.g using a small loop.

Ulcerative colitis increases the risk of bowel cancer.

Patients who have chronic inflammatory bowel disease, the so-called ulcerative colitis suffer, also are at increased risk for colon cancer. Ulcerative colitis is known as a precancerous condition. This term describes diseases that are considered as potential "preliminary stage" for the development of cancer. For this reason, needed regular check-ups in ulcerative colitis by colonoscopy.

The risk increases with family pressures already at a young age.

For certain family obligations, or inherited diseases, there is an increased risk of getting colon cancer:
  • People who have a particular gene, as evidenced so-called Hereditary Non-polyposes Colorectal Cancer (HNPCC gene), cancer to 80 - 90 percent of colon cancer. Conversely, at 10 to 15 percent of all cancer patients found that gene.
  • In some families, this often leads to benign tumors of the colon (adenomas), one speaks of "familial adenomatous polyposis coli. At the risk of colorectal cancer is affected by the transformation of benign tumors to malignant tumors in 70 percent. However, less than 1 percent of patients with colon cancer, such polyposis coli.
  • There are also some hereditary diseases in which occur particularly in the large intestine to the formation of benign adenomas. These can turn into cancer. These genetic diseases include Gardner's syndrome, in which the risk of malignancy is 85 percent, Turcot syndrome (about 70 per cent risk of malignancy), and the Peutz-Jeghers syndrome with only a low risk of malignancy.

Regular inspections are necessary.

Must be based on these family-related risks from the fact that the disease affected much earlier to cancer. Therefore, risk groups should have from 25 years of age once a year to an ultrasound examination every two years and perform an endoscopy.

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